Research Papers & Publications

Research

The Birmingham Research Unit of the Royal College of General Practitioners maintains a continuing programme of research in a wide and varied number of fields.  Historically, the Unit has collaborated with many institutions and organisations including the European Influenza Surveillance Scheme, Health Protection Agency (formerly the Public Health Laboratory Service), Meteorological Office, Department of Health, various academic departments, Prescription Pricing Authority and pharmaceutical companies. The Unit is most renowned for its work on respiratory diseases, particularly those caused by viruses such as influenza and respiratory syncytial virus.  Other areas of particular interest include infectious and intestinal diseases, asthma, allergic rhinitis (hay fever) chickenpox and herpes zoster (shingles).  The Unit welcomes informal discussions and proposals for future collaborations from outside sources. Please contact Dr Alex Elliot (aelliot@rcgpbhamresunit.nhs.uk) if there are any specific projects you would like to discuss.

Below are listed a number of special reports and the most recent publications produced by the Unit.

 

Special Reports

Our information leaflet, The Birmingham Research Unit, details the work of the Unit over the last 40 years. (pdf, 290Kb)

The Electronic Health Indicator Data (eHID) project is an EU funded project concerned with recording in-patient electronic medical records in a way that optimised the use of records for epidemiology. The project involved several networks throughout Europe including the Weekly Returns Service of the Birmingham Research Unit. (pdf, 516Kb)

A Winter's Tale provides detailed information on general respiratory diseases and the problems they can cause to primary and secondary health care resources. (pdf, 1.7Mb)

The Occupational Morbidity Report is a joint project with the Health & Safety Executive which aims to obtain information on the frequency of various kinds of illness in different occupations and, from the results, identify specific links between illness and occupation. (pdf, 1.8Mb)

 

Submitted papers accepted for publication

  1. Elliot AJ, Fleming DM. Influenza and respiratory syncytial virus in the elderly. Expert Rev Vaccines (accepted Jan 2008).
  2. Elliot AJ, Cross KW, Fleming DM. Acute respiratory infections and winter pressures on hospital admissions in England and Wales 1990-2005. J Pubic Health (accepted Dec 2007).

Publications (2004 – 2008)

1.      Fleming DM, Elliot AJ. Respiratory syncytial virus: a sleeping giant? Eur Respir J. 2007;30(6):1029-31. [Medline]

2.      Fleming DM, Elliot AJ. Lessons from 40 years' surveillance of influenza in England and Wales. Epidemiol Infect. 2007;doi:10.1017/S0950268807009910. [Medline]

3.      Cooper DL, Verlander N, Joseph C, Elliot AJ, Smith GE. Can syndromic thresholds provide early warning of national influenza outbreaks? J Pubic Health; doi:10.1093/pubmed/fdm068. [Medline]

4.      Fleming DM. The state of play in the battle against antimicrobial resistance: a general practitioner perspective. J Antimicrob Chemother. 2007;60 Suppl 1:i49-52. [Medline]

5.      Fleming DM, Elliot AJ, Kendall H. Skin infections and antibiotic prescribing: a comparison of surveillance and prescribing data. Br J Gen Pract. 2007;57(540):569-73. [Medline]

6.      Downs AM, Ross AM, Fleming DM, Coles GC. A downturn in the incidence of head lice infestation? Int J Dermatol. 2007;46(6):660-1. [Medline]

7.      Arkema JM, Meerhoff TJ, Paget WJ, Meijer A, Ansaldi F, Buchholz U, Fleming D, Nicoll A, van der Velden J. Seasonal influenza activity in Europe: declining in most countries in the West but increasing in the North-East. Euro Surveill. 2007;12(3):E070308.3. [Medline] [Free Full Text]

8.      Olowokure B, Clarke L, Elliot AJ, Harding D, Fleming A. Mumps and the media: changes in the reporting of mumps in response to newspaper coverage. J Epidemiol Commun Health 2007;61:385-388. [Medline]

9.      Arkema JM, Paget WJ, Meijer A, Meerhoff TJ, Ansaldi F, Buchholz U, Fleming D, Nicoll A, van der Velden J. Seasonal influenza beginning in Europe: report from EISS. Euro Surveill. 2007;12(1):E070125.3. [Medline] [Free Full Text]

10.   Fleming DM, Elliot AJ. Correspondence; epidemic influenza and vitamin D. Epidemiol Infect 2007;135(7):1091-2. [Medline]

11.   Fleming DM, Elliot AJ. The management of acute bronchitis in children. Expert Opin Pharmacother. 2007;8(4):415-26. [Medline]

12.   Fleming DM, Elliot AJ, Cross KW. Morbidity profiles of patients consulting during influenza and respiratory syncytial virus active periods. Epidemiol Infect 2007;135(7):1099-108. [Medline]

13.   Fleming DM, Elliot AJ. Changing disease incidence: the consulting room perspective. Brit J Gen Pract 2006;56(532):820-824. [Medline]

14.   Simms I, Fleming DM, Lowndes CM, Smith GE, Chapman RS. Surveillance of sexually transmitted diseases in general practice: a description of trends in the Royal College of General Practitioners Weekly Returns Service between 1994 and 2001. Int J STD AIDS 2006;17(10):693-8. [Medline]

15.   Deckers JG, Schellevis FG, Fleming DM. WHO diagnostic criteria as a validation tool for the diagnosis of diabetes mellitus: A study in five European countries. Eur J Gen Pract 2006;12(3):108-113. [Medline]

16.   Elliot AJ, Fleming DM. Surveillance of influenza-like illness in England and Wales during 1967-2006. Euro Surveill 2006;11(10):249-250.". [Medline] [Free Full Text]

17.   Elliot AJ, Cross KW, Smith GE, Burgess IF, Fleming DM. The association between impetigo, insect bites and air temperature: a retrospective 5-year study (1999-2003) using morbidity data collected from a sentinel general practice network database. Fam Pract 2006;23:490-496. [Medline]

18.   Fleming DM, Crovari P, Wahn U, Klemola T, Schlesinger Y, Langussis A, Oymar K, Garcia ML, Krygier A, Costa H, Heininger U, Pregaldien JL, Cheng SM, Skinner J, Razmpour A, Saville M, Gruber WC, Forrest B; CAIV-T Asthma Study Group. Comparison of the efficacy and safety of live attenuated cold-adapted influenza vaccine, trivalent, with trivalent inactivated influenza virus vaccine in children and adolescents with asthma. Pediatr Infect Dis J 2006;25(10):860-869. [Medline]

19.   Meerhoff TJ, Fleming D, Smith A, Mosnier A, van Gageldonk-Lafeber AB, Paget WJ. Surveillance recommendations based on an exploratory analysis of respiratory syncytial virus reports derived from the European Influenza Surveillance System. BMC Infect Dis 2006;6:128. [Medline] [Free Full Text]

20.   Viboud C, Tam T, Fleming D, Handel A, Miller MA, Simonsen L. Transmissibility and mortality impact of epidemic and pandemic influenza, with emphasis on the unusually deadly 1951 epidemic. Vaccine. 2006;24(44-46):6701-7. [Medline]

21.   Fleming DM, Elliot AJ. Estimating the risk population in relation to influenza vaccination policy. Vaccine 2006;24(20):4378-85. [Medline]

22.   Viboud C, Tam T, Fleming D, Miller MA, Simonsen L. 1951 influenza epidemic, England and Wales, Canada, and the United States. Emerg Infect Dis 2006;12(4):661-8. [Medline]

23.   Deckers JG, Paget WJ, Schellevis FG, Fleming DM. European primary care surveillance networks: their structure and operation. Fam Pract 2006;23(2):151-8. [Medline]

24.   Pannell RS, Fleming DM, Cross KW. The incidence of molluscum contagiosum, scabies and lichen planus. Epidemiol Infect 2005;133(6):985-91. [Medline]

25.   Fleming D. Influenza pandemics and avian flu. BMJ 2005;331(7524):1066-9. [Medline]

26.   Gani R, Hughes H, Fleming D, Griffin T, Medlock J, Leach S. Potential impact of antiviral drug use during influenza pandemic. Emerg Infect Dis. 2005;11(9):1355-62. [Medline] [Free Full Text]

27.   Fleming DM, Cross KW, Barley MA. Recent changes in the prevalence of diseases presenting for health care. Br J Gen Pract 2005;55(517):589-95. [Medline] [Free Full Text]

28.   Fleming DM, Elliot AJ. The impact of influenza on the health and health care utilisation of elderly people. Vaccine 2005. [Medline]

29.   Fleming DM, Pannell RS, Elliot AJ, Cross KW. Respiratory illness associated with influenza and respiratory syncytial virus infection. Arch Dis Child 2005. [Medline] [Free Full Text]

30.   Fleming DM, Pannell RS, Cross KW. Mortality in children from influenza and respiratory syncytial virus. J Epidemiol Community Health 2005;59(7):586-90. [Medline] [Free Full Text]

31.   Fleming DM, Ross AM, Cross KW, Kendall H, Elliot AJ. Concerning: 'Why has antibiotic prescribing for respiratory illness declined in primary care? A longitudinal study using the General Practice Research Database'. J Public Health (Oxf) 2005;27(2):228-9. [Medline]

32.   Fleming DM, Cross KW, Pannell RS. Influenza and its relationship to circulatory disorders. Epidemiol Infect 2005;133(2):255-62. [Medline]

33.   Fleming DM, Elliot AJ. Children with 'flu: not to be sniffed at. Br J Gen Pract 2005;55(512):231-2. [Medline] [Free Full Text]

34.   Fleming DM, Soler JK. Using electronic medical records for research. Eur J Gen Pract 2005;11(1):2-4. [Medline]

35.   Donker GA, Fleming DM, Schellevis FG, Spreeuwenberg P. Differences in treatment regimes, consultation frequency and referral patterns of diabetes mellitus in general practice in five European countries. Fam Pract 2004;21(4):364-9. [Medline] [Free Full Text]

36.   Davey P, Donnan P, Fleming D, Wise R, Woodhead M. Association between antibiotic prescribing trends in general practice and community-acquired pneumonia mortality. Respir Med 2004;98(8):798-800; author reply 1-3. [Medline]

37.   Ross A, Fleming D. Hayfever--practical management issues. Br J Gen Pract 2004;54(503):412-4. [Medline] [Free Full Text]

38.   Woodhead M, Fleming D, Wise R. Antibiotics, resistance, and clinical outcomes. BMJ 2004;328(7451):1270-1. [Medline] [Free Full Text]

39.   Sunderland RS, Fleming DM. Continuing decline in acute asthma episodes in the community. Arch Dis Child 2004;89(3):282-5. [Medline] [Free Full Text]

40.   Fleming DM, Barley MA, Chapman RS. Surveillance of the bioterrorist threat: a primary care response. Commun Dis Public Health 2004;7(1):68-72. [Medline]

41.   Fleming DM, Schellevis FG, Van Casteren V. The prevalence of known diabetes in eight European countries. Eur J Public Health 2004;14(1):10-4. [Medline]

42.   Harcourt SE, Edwards DE, Fleming DM, Smith RL, Smith GE. How representative is the population covered by the RCGP spotter practice scheme? Using Geographical Information Systems to assess. J Public Health (Oxf) 2004;26(1):88-94. [Medline]

43.   Fleming DM, Cross KW, Cobb WA, Chapman RS. Gender difference in the incidence of shingles. Epidemiol Infect 2004;132(1):1-5. [Medline]

44.   Fleming DM, Bartelds A, Chapman RS, Cross KW. The consistency of shingles and its significance for health monitoring. Eur J Epidemiol 2004;19(12):1113-8. [Medline]

 

 

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